Does the Combination of Platelet-rich Plasma and Supervised Exercise Yield Better Pain Relief and Enhanced Function in Knee Osteoarthritis? A Randomized Controlled Trial
Background: Knee osteoarthritis is a leading cause of disability with substantial healthcare costs, and efficient nonsurgical treatment methods are still needed. Platelet- rich plasma (PRP) injections and exercise therapy are used frequently in clinical practice. Whether PRP or PRP combined with exercise is more effective than exercise alone is unclear. Questions/purposes (1) Which treatment relieves knee […]
Investigation of the synergistic effect of platelet-rich plasma and polychromatic light on human dermal fibroblasts seeded chitosan/gelatin scaffolds for wound healing
Conventional wound healing treatments are insufficient for chronic wounds caused by factors such as senescence of fibroblasts, reduced growth factor synthesis, and poor angiogenesis. Recently, tissue engineering approaches have been investigated to develop effective therapies. In this study, a biochemical/biophysical stimulant-based 3D system was developed for the healing of chronic wounds. In this direction, genipin […]
The impact of silver/beta-tricalcium phosphate nanocomposite combined with injectable platelet-rich fibrin on the healing of mandibular bone defects: An experimental study in dogs
This study examined the biological response of canine mandibular bone to synthetic nanocomposite material alone or combined with injectable platelet-rich fibrin i-PRF. Twelve healthy adult male local breed dogs aged 12 to 18 months and weighing 15-20 kg were used in this study. These dogs were divided into two main groups based on healing intervals […]
Enhanced Bioactive Potential of Functionalized Injectable Platelet-Rich Plasma
Injectable platelet-rich fibrin (iPRF) is a frequently used platelet concentrate used for various medical purposes both in veterinary and human medicine due to the regenerative potential of hard and soft tissues, and also because of its antimicrobial effectiveness. This in vitro study was carried out to assess the cumulative antimicrobial and antibiofilm effect of […]